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Population Dynamics of Epithelial-Mesenchymal Heterogeneity in Cancer Cells

Phenotypic heterogeneity is a hallmark of aggressive cancer behaviour and a clinical challenge. Despite much characterisation of this heterogeneity at a multi-omics level in many cancers, we have a limited understanding of how this heterogeneity emerges spontaneously in an isogenic cell population....

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Detalles Bibliográficos
Autores principales: Jain, Paras, Bhatia, Sugandha, Thompson, Erik W., Jolly, Mohit Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945776/
https://www.ncbi.nlm.nih.gov/pubmed/35327538
http://dx.doi.org/10.3390/biom12030348