The Pyrazolo[3,4-d]Pyrimidine Derivative Si306 Encapsulated into Anti-GD2-Immunoliposomes as Therapeutic Treatment of Neuroblastoma

Si306, a pyrazolo[3,4-d]pyrimidine derivative recently identified as promising anticancer agent, has shown favorable in vitro and in vivo activity profile against neuroblastoma (NB) models by acting as a competitive inhibitor of c-Src tyrosine kinase. Nevertheless, Si306 antitumor activity is associ...

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Detalles Bibliográficos
Autores principales: Rango, Enrico, Pastorino, Fabio, Brignole, Chiara, Mancini, Arianna, Poggialini, Federica, Di Maria, Salvatore, Zamperini, Claudio, Iovenitti, Giulia, Fallacara, Anna Lucia, Sabetta, Samantha, Clementi, Letizia, Valoti, Massimo, Schenone, Silvia, Angelucci, Adriano, Ponzoni, Mirco, Dreassi, Elena, Botta, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945814/
https://www.ncbi.nlm.nih.gov/pubmed/35327462
http://dx.doi.org/10.3390/biomedicines10030659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945814/
https://www.ncbi.nlm.nih.gov/pubmed/35327462
http://dx.doi.org/10.3390/biomedicines10030659

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