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Potential Metabolite Markers for Pancreatic Cancer Identified by Metabolomic Analysis of Induced Cancer-Associated Fibroblasts

SIMPLE SUMMARY: Fibroblasts in normal tissues conduct energy metabolism via oxidative phosphorylation (OXPHOS). However, cancer-associated fibroblasts (CAFs) produce energy (i.e., ATP) via glycolysis. Nonetheless, whether intracellular metabolism transitions from OXPHOS to glycolysis when normal tis...

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Detalles Bibliográficos
Autores principales: Miyazaki, Yoshihiro, Mori, Nobuhito, Akagi, Yuka, Oda, Tatsuya, Kida, Yasuyuki S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945883/
https://www.ncbi.nlm.nih.gov/pubmed/35326527
http://dx.doi.org/10.3390/cancers14061375