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Celastrol and Resveratrol Modulate SIRT Genes Expression and Exert Anticancer Activity in Colon Cancer Cells and Cancer Stem-like Cells

SIMPLE SUMMARY: The recovery rate in patients with metastatic colorectal cancer (CRC) remains low and declines with successive lines of treatment. This phenomenon is caused by the development of drug resistance and the presence of colorectal cancer stem cells (CSCs). Phytochemicals, like -celastrol...

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Detalles Bibliográficos
Autores principales: Moreira, Helena, Szyjka, Anna, Grzesik, Justyna, Pelc, Katarzyna, Żuk, Magdalena, Kulma, Anna, Emhemmed, Fathi, Muller, Christian D., Gąsiorowski, Kazimierz, Barg, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945991/
https://www.ncbi.nlm.nih.gov/pubmed/35326523
http://dx.doi.org/10.3390/cancers14061372