Cargando…

Celastrol and Resveratrol Modulate SIRT Genes Expression and Exert Anticancer Activity in Colon Cancer Cells and Cancer Stem-like Cells

SIMPLE SUMMARY: The recovery rate in patients with metastatic colorectal cancer (CRC) remains low and declines with successive lines of treatment. This phenomenon is caused by the development of drug resistance and the presence of colorectal cancer stem cells (CSCs). Phytochemicals, like -celastrol...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moreira, Helena, Szyjka, Anna, Grzesik, Justyna, Pelc, Katarzyna, Żuk, Magdalena, Kulma, Anna, Emhemmed, Fathi, Muller, Christian D., Gąsiorowski, Kazimierz, Barg, Ewa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8945991/ https://www.ncbi.nlm.nih.gov/pubmed/35326523 http://dx.doi.org/10.3390/cancers14061372

Ejemplares similares

Combination of Irinotecan and Melatonin with the Natural Compounds Wogonin and Celastrol for Colon Cancer Treatment
por: Radajewska, Anna, et al.
Publicado: (2023)

Chemopreventive activity of celastrol in drug–resistant human colon carcinoma cell cultures
por: Moreira, Helena, et al.
Publicado: (2018)

Prooxidative Activity of Celastrol Induces Apoptosis, DNA Damage, and Cell Cycle Arrest in Drug-Resistant Human Colon Cancer Cells
por: Moreira, Helena, et al.
Publicado: (2019)

Anticancer and Antioxidant Activities in Ganoderma lucidum Wild Mushrooms in Poland, as Well as Their Phenolic and Triterpenoid Compounds
por: Kolniak-Ostek, Joanna, et al.
Publicado: (2022)

Emulsions Made of Oils from Seeds of GM Flax Protect V79 Cells against Oxidative Stress
por: Skorkowska-Telichowska, Katarzyna, et al.
Publicado: (2016)

Celastrol exerts anti‐inflammatory effect in liver fibrosis via activation of AMPK‐SIRT3 signalling
por: Wang, Yuqin, et al.
Publicado: (2019)

Synthesis and characterisation of celastrol derivatives as potential anticancer agents
por: Zhang, Hong-Jian, et al.
Publicado: (2017)

Synthesis and anticancer properties of celastrol derivatives involved in the inhibition of VEGF
por: Song, Mingxia, et al.
Publicado: (2023)

Celastrol and Melatonin Modify SIRT1, SIRT6 and SIRT7 Gene Expression and Improve the Response of Human Granulosa-Lutein Cells to Oxidative Stress
por: Martín-Ramírez, Rita, et al.
Publicado: (2021)

Celastrol: A Review of Useful Strategies Overcoming its Limitation in Anticancer Application
por: Shi, Jinfeng, et al.
Publicado: (2020)

A Phenylacetamide Resveratrol Derivative Exerts Inhibitory Effects on Breast Cancer Cell Growth
por: Chimento, Adele, et al.
Publicado: (2021)

The Effect of Metalloestrogens on the Effectiveness of Aromatase Inhibitors in a Hormone-Dependent Breast Cancer Cell Model
por: Boszkiewicz, Kamila, et al.
Publicado: (2023)

Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1
por: Zhang, Yinliang, et al.
Publicado: (2016)

Sirt1 Is Required for Resveratrol-Mediated Chemopreventive Effects in Colorectal Cancer Cells
por: Buhrmann, Constanze, et al.
Publicado: (2016)

Anticancer Molecular Mechanisms of Resveratrol
por: Varoni, Elena M., et al.
Publicado: (2016)

Upregulating Noxa by ER Stress, Celastrol Exerts Synergistic Anti-Cancer Activity in Combination with ABT-737 in Human Hepatocellular Carcinoma Cells
por: Zhu, Hong, et al.
Publicado: (2012)

Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia–reperfusion
por: Liu, Dan-Dan, et al.
Publicado: (2021)

Resveratrol and SIRT1: Antiaging Cornerstones for Oocytes?
por: Grzeczka, Arkadiusz, et al.
Publicado: (2022)

Resveratrol-like Compounds as SIRT1 Activators
por: Ciccone, Lidia, et al.
Publicado: (2022)

Nanoencapsulation of natural triterpenoid celastrol for prostate cancer treatment
por: Sanna, Vanna, et al.
Publicado: (2015)

Celastrol Enhances the Anti-Liver Cancer Activity of Sorafenib
por: Zhang, Rui, et al.
Publicado: (2019)

Celastrol-conjugated chitosan oligosaccharide for the treatment of pancreatic cancer
por: Zeng, Xiaohu, et al.
Publicado: (2021)

Synergistic anticancer effects of triptolide and celastrol, two main compounds from thunder god vine
por: Jiang, Qi-Wei, et al.
Publicado: (2015)

Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids
por: Wang, Huabo, et al.
Publicado: (2015)

Systematic identification of Celastrol-binding proteins reveals that Shoc2 is inhibited by Celastrol
por: Xiao-pei, Huang, et al.
Publicado: (2018)

Flavonoid C-glucosides Derived from Flax Straw Extracts Reduce Human Breast Cancer Cell Growth In vitro and Induce Apoptosis
por: Czemplik, Magdalena, et al.
Publicado: (2016)

Sirt1 activation by resveratrol is substrate sequence-selective
por: Lakshminarasimhan, Mahadevan, et al.
Publicado: (2013)

Activation of SIRT1 by Resveratrol requires lamin A
por: Liu, Baohua, et al.
Publicado: (2013)

Unraveling the Anticancer Effect of Curcumin and Resveratrol
por: Pavan, Aline Renata, et al.
Publicado: (2016)

3-Hydroxybutyrate Is Active Compound in Flax that Upregulates Genes Involved in DNA Methylation
por: Mierziak, Justyna, et al.
Publicado: (2020)

Correction: Systematic identification of celastrol-binding proteins reveals that Shoc2 is inhibited by celastrol
Publicado: (2021)

Celastrol inhibits gastric cancer growth by induction of apoptosis and autophagy
por: Lee, Hyun-Woo, et al.
Publicado: (2014)

Celastrol Inhibits the Growth of Ovarian Cancer Cells in vitro and in vivo
por: Xu, Li-Na, et al.
Publicado: (2019)

Luteolin exerts an anticancer effect on NCI-H460 human non-small cell lung cancer cells through the induction of Sirt1-mediated apoptosis
por: MA, LIPING, et al.
Publicado: (2015)

Were our Ancestors Right in Using Flax Dressings? Research on the Properties of Flax Fibre and Its Usefulness in Wound Healing
por: Gębarowski, Tomasz, et al.
Publicado: (2020)

Aucubin Exerts Anticancer Activity in Breast Cancer and Regulates Intestinal Microbiota
por: Shao, Min, et al.
Publicado: (2022)

Celastrol Attenuates the Invasion and Migration and Augments the Anticancer Effects of Bortezomib in a Xenograft Mouse Model of Multiple Myeloma
por: Shanmugam, Muthu K., et al.
Publicado: (2018)

Flavonoid engineering of flax potentiate its biotechnological application
por: Żuk, Magdalena, et al.
Publicado: (2011)

Correction: Flavonoid engineering of flax potentiate its biotechnological application
por: Żuk, Magdalena, et al.
Publicado: (2012)

Radioprotective and Antioxidant Effect of Resveratrol in Hippocampus by Activating Sirt1
por: Li, Jianguo, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_otf6f2hbl13ndq669an43tgcpf