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Spreading of Alpha Synuclein from Glioblastoma Cells towards Astrocytes Correlates with Stem-like Properties

SIMPLE SUMMARY: The present study questions whether cells from glioblastoma multiforme (GBM), which overexpress α-synuclein (α-syn), may alter neighboring non-tumoral astrocyte cell lines. The occurrence of α-syn in GBM correlates with the expression of the stem cell marker nestin. When astrocytes a...

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Detalles Bibliográficos
Autores principales: Ryskalin, Larisa, Biagioni, Francesca, Morucci, Gabriele, Busceti, Carla L., Frati, Alessandro, Puglisi-Allegra, Stefano, Ferrucci, Michela, Fornai, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946011/
https://www.ncbi.nlm.nih.gov/pubmed/35326570
http://dx.doi.org/10.3390/cancers14061417