Optogenetic Control of Engrafted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Live Mice: A Proof-of-Concept Study

Background: Cellular transplantation has emerged as promising approach for treating cardiac diseases. However, a poor engraftment rate limits our understanding on how transplanted cardiomyocytes contribute to cardiac function in the recipient’s heart. Methods: The CRISPR/Cas9 technique was employed...

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Detalles Bibliográficos
Autores principales: Joshi, Jyotsna, Xu, Bing, Rubart, Michael, Chang, Yun, Bao, Xiaoping, Chaliki, Hari P., Scott, Luis R., Zhu, Wuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946017/
https://www.ncbi.nlm.nih.gov/pubmed/35326403
http://dx.doi.org/10.3390/cells11060951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946017/
https://www.ncbi.nlm.nih.gov/pubmed/35326403
http://dx.doi.org/10.3390/cells11060951

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