Early On-Treatment Prediction of the Mechanisms of Acquired Resistance to EGFR Tyrosine Kinase Inhibitors

SIMPLE SUMMARY: EGFR T790M-positive clones expand in treated by EGFR inhibitors. C-MET amplified clones expand in HCC827 lung cancer cells treated by EGFR inhibitors. Early on-treatment kinetics of the resistance-related gene predict the resistance mechanism. ABSTRACT: Background: Prediction of resi...

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Detalles Bibliográficos
Autores principales: Choi, Yu-ra, Cho, Youngnam, Park, Seog-Yun, Kim, Sunshin, Shin, Myungsun, Choi, Yongdoo, Shin, Dong Hoon, Han, Ji-Youn, Lee, Youngjoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946020/
https://www.ncbi.nlm.nih.gov/pubmed/35326664
http://dx.doi.org/10.3390/cancers14061512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946020/
https://www.ncbi.nlm.nih.gov/pubmed/35326664
http://dx.doi.org/10.3390/cancers14061512

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