Cargando…

Vav1 Promotes B-Cell Lymphoma Development

Vav1 is normally and exclusively expressed in the hematopoietic system where it functions as a specific GDP/GTP nucleotide exchange factor (GEF), firmly regulated by tyrosine phosphorylation. Mutations and overexpression of Vav1 in hematopoietic malignancies, and in human cancers of various histolog...

Descripción completa

Detalles Bibliográficos
Autores principales: Shalom, Batel, Farago, Marganit, Salaymeh, Yaser, Sebban, Shulamit, Pikarsky, Eli, Katzav, Shulamit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946024/
https://www.ncbi.nlm.nih.gov/pubmed/35326399
http://dx.doi.org/10.3390/cells11060949