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Conversion of a Non-Cancer-Selective Promoter into a Cancer-Selective Promoter

SIMPLE SUMMARY: The rat progression elevated gene-3 (PEG-3) promoter displays cancer-selective expression, whereas the rat growth arrest and DNA damage inducible gene-34 (GADD34) promoter lacks cancer specificity. PEG-3 and GADD34 minimal promoters display strong sequence homology except for two sin...

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Detalles Bibliográficos
Autores principales: Bhoopathi, Praveen, Pradhan, Anjan K., Kumar, Amit, Maji, Santanu, Mannangatti, Padmanabhan, Deng, Xiaoyan, Bandyopadhyay, Dipankar, Sarkar, Devanand, Wang, Xiang-Yang, Landry, Joseph W., Das, Swadesh K., Emdad, Luni, Fisher, Paul B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946048/
https://www.ncbi.nlm.nih.gov/pubmed/35326649
http://dx.doi.org/10.3390/cancers14061497