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Distinct and Common Features of Numerical and Structural Chromosomal Instability across Different Cancer Types

SIMPLE SUMMARY: Many cancer cells are chromosomally unstable, a phenotype describing a tendency for accumulating chromosomal aberrations. Entire chromosomes tend to be gained or lost, which is called whole chromosome instability (W-CIN). Structural chromosomal instability (S-CIN) describes an increa...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoxiao, Kschischo, Maik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946057/
https://www.ncbi.nlm.nih.gov/pubmed/35326573
http://dx.doi.org/10.3390/cancers14061424