Dramatic In Vivo Efficacy of the EZH2-Inhibitor Tazemetostat in PBRM1-Mutated Human Chordoma Xenograft

SIMPLE SUMMARY: Chordomas are rare bone tumors characterized by a high recurrence rate. Presently, no medical treatment is available for advanced diseases due to the lack of molecular data and preclinical models. The current study showed the establishment and characterization of the largest panel ch...

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Detalles Bibliográficos
Autores principales: Passeri, Thibault, Dahmani, Ahmed, Masliah-Planchon, Julien, Naguez, Adnan, Michou, Marine, El Botty, Rania, Vacher, Sophie, Bouarich, Rachida, Nicolas, André, Polivka, Marc, Franck, Coralie, Schnitzler, Anne, Némati, Fariba, Roman-Roman, Sergio, Bourdeaut, Franck, Adle-Biassette, Homa, Mammar, Hamid, Froelich, Sébastien, Bièche, Ivan, Decaudin, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946089/
https://www.ncbi.nlm.nih.gov/pubmed/35326637
http://dx.doi.org/10.3390/cancers14061486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946089/
https://www.ncbi.nlm.nih.gov/pubmed/35326637
http://dx.doi.org/10.3390/cancers14061486

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