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Targeting Proliferating Tumor-Infiltrating Macrophages Facilitates Spatial Redistribution of CD8(+) T Cells in Pancreatic Cancer

SIMPLE SUMMARY: Current studies aim to target tumor-associated macrophages (TAMs) to alleviate immunosuppression and inhibit tumor growth. However, the specific mechanisms that drive TAMs to impede T cell migration into and within tumors are still unclear. Here, we found that after pancreatic ductal...

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Detalles Bibliográficos
Autores principales: Yang, Xiaobao, Lin, Jinrong, Wang, Guanzheng, Xu, Dakang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946118/
https://www.ncbi.nlm.nih.gov/pubmed/35326625
http://dx.doi.org/10.3390/cancers14061474