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Aldehyde Trapping by ADX-102 Is Protective against Cigarette Smoke and Alcohol Mediated Lung Cell Injury

Most individuals diagnosed with alcohol use disorders smoke cigarettes. Large concentrations of malondialdehyde and acetaldehyde are found in lungs co-exposed to cigarette smoke and alcohol. Aldehydes directly injure lungs and form aldehyde protein adducts, impacting epithelial functions. Recently,...

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Detalles Bibliográficos
Autores principales: Ochoa, Carmen A., Nissen, Claire G., Mosley, Deanna D., Bauer, Christopher D., Jordan, Destiny L., Bailey, Kristina L., Wyatt, Todd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946168/
https://www.ncbi.nlm.nih.gov/pubmed/35327585
http://dx.doi.org/10.3390/biom12030393