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Acetylation, Phosphorylation, Ubiquitination (Oh My!): Following Post-Translational Modifications on the Ubiquitin Road

Ubiquitination is controlled by a series of E1, E2, and E3 enzymes that can ligate ubiquitin to cellular proteins and dictate the turnover of a substrate and the outcome of signalling events such as DNA damage repair and cell cycle. This process is complex due to the combinatorial power of ~35 E2 an...

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Detalles Bibliográficos
Autores principales: Lacoursiere, Rachel E., Hadi, Dania, Shaw, Gary S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946176/
https://www.ncbi.nlm.nih.gov/pubmed/35327659
http://dx.doi.org/10.3390/biom12030467