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Evaluation of Hydroxycarboxylic Acid Receptor 1 (HCAR1) as a Building Block for Genetically Encoded Extracellular Lactate Biosensors

The status of lactate has evolved from being considered a waste product of cellular metabolism to a useful metabolic substrate and, more recently, to a signaling molecule. The fluctuations of lactate levels within biological tissues, in particular in the interstitial space, are crucial to assess wit...

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Detalles Bibliográficos
Autores principales: Wellbourne-Wood, Joel, Briquet, Marc, Alessandri, Maxime, Binda, Francesca, Touya, Maylis, Chatton, Jean-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946183/
https://www.ncbi.nlm.nih.gov/pubmed/35323413
http://dx.doi.org/10.3390/bios12030143