Inherited Retinal Degeneration: PARP-Dependent Activation of Calpain Requires CNG Channel Activity

Inherited retinal degenerations (IRDs) are a group of blinding diseases, typically involving a progressive loss of photoreceptors. The IRD pathology is often based on an accumulation of cGMP in photoreceptors and associated with the excessive activation of calpain and poly (ADP-ribose) polymerase (P...

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Detalles Bibliográficos
Autores principales: Yan, Jie, Günter, Alexander, Das, Soumyaparna, Mühlfriedel, Regine, Michalakis, Stylianos, Jiao, Kangwei, Seeliger, Mathias W., Paquet-Durand, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946186/
https://www.ncbi.nlm.nih.gov/pubmed/35327647
http://dx.doi.org/10.3390/biom12030455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946186/
https://www.ncbi.nlm.nih.gov/pubmed/35327647
http://dx.doi.org/10.3390/biom12030455

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