Continuous Low-Intensity Ultrasound Preserves Chondrogenesis of Mesenchymal Stromal Cells in the Presence of Cytokines by Inhibiting NFκB Activation

Proinflammatory joint environment, coupled with impeded chondrogenic differentiation of mesenchymal stromal cells (MSCs), led to inferior cartilage repair outcomes. Nuclear translocation of phosphorylated-NFκB downregulates SOX9 and hinders the chondrogenesis of MSCs. Strategies that minimize the de...

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Detalles Bibliográficos
Autores principales: Bhogoju, Sarayu, Khan, Shahid, Subramanian, Anuradha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946190/
https://www.ncbi.nlm.nih.gov/pubmed/35327626
http://dx.doi.org/10.3390/biom12030434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946190/
https://www.ncbi.nlm.nih.gov/pubmed/35327626
http://dx.doi.org/10.3390/biom12030434

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