Cargando…

Calystegines Improve the Metabolic Activity of Human Adipose Derived Stromal Stem Cells (ASCs) under Hyperglycaemic Condition through the Reduction of Oxidative/ER Stress, Inflammation, and the Promotion of the AKT/PI3K/mTOR Pathway

Hyperglycaemia and its resulting glucotoxicity are among the most prominent hallmarks of diabetes mellitus (DM) development. Persistent hyperglycaemia further leads to oxidative stress via mitochondrial dysfunction and subsequent ER stress onset, while associated hyperlipidaemia triggers the adipose...

Descripción completa

Detalles Bibliográficos
Autores principales: Kowalczuk, Anna, Bourebaba, Nabila, Panchuk, Juliia, Marycz, Krzysztof, Bourebaba, Lynda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946193/
https://www.ncbi.nlm.nih.gov/pubmed/35327652
http://dx.doi.org/10.3390/biom12030460