Targeting the DNA Damage Response Pathway as a Novel Therapeutic Strategy in Colorectal Cancer

SIMPLE SUMMARY: Defective DNA damage response (DDR) is a hallmark of cancer leading to genomic instability. Up to 15–20% of colorectal cancers carry alterations in DDR. However, the role of DDR alterations as a prognostic factor and as a therapeutic target must be elucidated. To date, disappointing...

Descripción completa

Detalles Bibliográficos
Autores principales: Catalano, Fabio, Borea, Roberto, Puglisi, Silvia, Boutros, Andrea, Gandini, Annalice, Cremante, Malvina, Martelli, Valentino, Sciallero, Stefania, Puccini, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946235/
https://www.ncbi.nlm.nih.gov/pubmed/35326540
http://dx.doi.org/10.3390/cancers14061388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946235/
https://www.ncbi.nlm.nih.gov/pubmed/35326540
http://dx.doi.org/10.3390/cancers14061388

Ejemplares similares