A Cell Double-Barcoding System for Quantitative Evaluation of Primary Tumors and Metastasis in Animals That Uncovers Clonal-Specific Anti-Cancer Drug Effects

SIMPLE SUMMARY: The main problem in treating advanced cancers is a metastatic spread when individual cancer cells leave the primary tumor and colonize to distant organs. In drug development, it is important to quantitatively assess effects of novel drug candidates on both primary tumors and metastas...

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Detalles Bibliográficos
Autores principales: Hesin, Arkadi, Kumar, Santosh, Gahramanov, Valid, Becker, Maria, Vilenchik, Maria, Alexandrov, Ilya, Yaglom, Julia, Sherman, Michael Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946264/
https://www.ncbi.nlm.nih.gov/pubmed/35326533
http://dx.doi.org/10.3390/cancers14061381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946264/
https://www.ncbi.nlm.nih.gov/pubmed/35326533
http://dx.doi.org/10.3390/cancers14061381

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