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A Cell Double-Barcoding System for Quantitative Evaluation of Primary Tumors and Metastasis in Animals That Uncovers Clonal-Specific Anti-Cancer Drug Effects
SIMPLE SUMMARY: The main problem in treating advanced cancers is a metastatic spread when individual cancer cells leave the primary tumor and colonize to distant organs. In drug development, it is important to quantitatively assess effects of novel drug candidates on both primary tumors and metastas...
Autores principales: | Hesin, Arkadi, Kumar, Santosh, Gahramanov, Valid, Becker, Maria, Vilenchik, Maria, Alexandrov, Ilya, Yaglom, Julia, Sherman, Michael Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946264/ https://www.ncbi.nlm.nih.gov/pubmed/35326533 http://dx.doi.org/10.3390/cancers14061381 |
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