PD-L1 Silencing in Liver Using siRNAs Enhances Efficacy of Therapeutic Vaccination for Chronic Hepatitis B

In chronic hepatitis B virus (HBV) infection, virus-specific T cells are scarce and partially dysfunctional. Therapeutic vaccination is a promising strategy to induce and activate new virus-specific T cells. In long-term or high-level HBV carriers, however, therapeutic vaccination by itself may not...

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Detalles Bibliográficos
Autores principales: Bunse, Till, Kosinska, Anna D., Michler, Thomas, Protzer, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946278/
https://www.ncbi.nlm.nih.gov/pubmed/35327662
http://dx.doi.org/10.3390/biom12030470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946278/
https://www.ncbi.nlm.nih.gov/pubmed/35327662
http://dx.doi.org/10.3390/biom12030470

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