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PD-L1 Silencing in Liver Using siRNAs Enhances Efficacy of Therapeutic Vaccination for Chronic Hepatitis B

In chronic hepatitis B virus (HBV) infection, virus-specific T cells are scarce and partially dysfunctional. Therapeutic vaccination is a promising strategy to induce and activate new virus-specific T cells. In long-term or high-level HBV carriers, however, therapeutic vaccination by itself may not...

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Detalles Bibliográficos
Autores principales:	Bunse, Till, Kosinska, Anna D., Michler, Thomas, Protzer, Ulrike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946278/ https://www.ncbi.nlm.nih.gov/pubmed/35327662 http://dx.doi.org/10.3390/biom12030470

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