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Sequestration of Intestinal Acidic Toxins by Cationic Resin Attenuates Pancreatic Cancer Progression through Promoting Autophagic Flux for YAP Degradation

SIMPLE SUMMARY: Annually, more than 450,000 people are diagnosed with pancreatic cancer worldwide with over 430,000 mortalities. Pancreatic ductal carcinoma (PDAC) accounts for around 80% of pancreatic cancer cases with an extremely high mortality rate. Emerging research has demonstrated that gut dy...

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Detalles Bibliográficos
Autores principales: Zhao, Guangfu, Zhang, Tianci, Liu, Wei, Edderkaoui, Mouad, Hu, Richard, Li, Jun, Pandol, Stephen J., Fu, Xiangsheng, Han, Yuan-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946475/
https://www.ncbi.nlm.nih.gov/pubmed/35326559
http://dx.doi.org/10.3390/cancers14061407