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GM-CSF Protects Macrophages from DNA Damage by Inducing Differentiation

At inflammatory loci, pro-inflammatory activation of macrophages produces large amounts of reactive oxygen species (ROS) that induce DNA breaks and apoptosis. Given that M-CSF and GM-CSF induce two different pathways in macrophages, one for proliferation and the other for survival, in this study we...

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Detalles Bibliográficos
Autores principales: Vico, Tania, Youssif, Catrin, Zare, Fathema, Comalada, Mònica, Sebastian, Carlos, Lloberas, Jorge, Celada, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946476/
https://www.ncbi.nlm.nih.gov/pubmed/35326386
http://dx.doi.org/10.3390/cells11060935