Cargando…
GM-CSF Protects Macrophages from DNA Damage by Inducing Differentiation
At inflammatory loci, pro-inflammatory activation of macrophages produces large amounts of reactive oxygen species (ROS) that induce DNA breaks and apoptosis. Given that M-CSF and GM-CSF induce two different pathways in macrophages, one for proliferation and the other for survival, in this study we...
Autores principales: | Vico, Tania, Youssif, Catrin, Zare, Fathema, Comalada, Mònica, Sebastian, Carlos, Lloberas, Jorge, Celada, Antonio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946476/ https://www.ncbi.nlm.nih.gov/pubmed/35326386 http://dx.doi.org/10.3390/cells11060935 |
Ejemplares similares
-
Mitogen-Activated Protein Kinases and Mitogen Kinase Phosphatase 1: A Critical Interplay in Macrophage Biology
por: Lloberas, Jorge, et al.
Publicado: (2016) -
GM-CSF Dependent Differential Control of Mycobacterium tuberculosis Infection in Human and Mouse Macrophages: Is Macrophage Source of GM-CSF Critical to Tuberculosis Immunity?
por: Mishra, Abhishek, et al.
Publicado: (2020) -
Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment
por: Bosteels, Cedric, et al.
Publicado: (2022) -
Distinct Responses to IL4 in Macrophages Mediated by JNK
por: Arpa, Luís, et al.
Publicado: (2023) -
Myeloid p38α signaling promotes intestinal IGF‐1 production and inflammation‐associated tumorigenesis
por: Youssif, Catrin, et al.
Publicado: (2018)