Structural Comparative Modeling of Multi-Domain F508del CFTR

Cystic fibrosis (CF) is a rare genetic disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR), an epithelial anion channel expressed in several vital organs. Absence of functional CFTR results in imbalanced osmotic equilibrium and subsequent mucus build up in t...

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Detalles Bibliográficos
Autores principales: McDonald, Eli Fritz, Woods, Hope, Smith, Shannon T., Kim, Minsoo, Schoeder, Clara T., Plate, Lars, Meiler, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946492/
https://www.ncbi.nlm.nih.gov/pubmed/35327663
http://dx.doi.org/10.3390/biom12030471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946492/
https://www.ncbi.nlm.nih.gov/pubmed/35327663
http://dx.doi.org/10.3390/biom12030471

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