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A Brief Overview of Adaptive Designs for Phase I Cancer Trials

SIMPLE SUMMARY: Phase I cancer trials are important for new drug developments to test the safety and optimal dosage of cancer drugs which are usually toxic. Understanding biostatistical methodologies of these designs is important for developing phase I studies that are both safe for the participants...

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Detalles Bibliográficos
Autores principales: Saxena, Anshul, Rubens, Muni, Ramamoorthy, Venkataraghavan, Zhang, Zhenwei, Ahmed, Md Ashfaq, McGranaghan, Peter, Das, Sankalp, Veledar, Emir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946506/
https://www.ncbi.nlm.nih.gov/pubmed/35326715
http://dx.doi.org/10.3390/cancers14061566