Inhibition of STAT6 Activation by AS1517499 Inhibits Expression and Activity of PPARγ in Macrophages to Resolve Acute Inflammation in Mice

Signal transducer and activator of transcription 6 (STAT6) promotes an anti-inflammatory process by inducing the development of M2 macrophages. We investigated whether modulating STAT6 activity in macrophages using AS1517499, the specific STAT6 inhibitor, affects the restoration of homeostasis after...

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Detalles Bibliográficos
Autores principales: Lee, Ye-Ji, Kim, Kiyoon, Kim, Minsuk, Ahn, Young-Ho, Kang, Jihee Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946515/
https://www.ncbi.nlm.nih.gov/pubmed/35327639
http://dx.doi.org/10.3390/biom12030447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946515/
https://www.ncbi.nlm.nih.gov/pubmed/35327639
http://dx.doi.org/10.3390/biom12030447

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