Targeting the Non-Canonical NF-κB Pathway in Chronic Lymphocytic Leukemia and Multiple Myeloma

SIMPLE SUMMARY: This study was designed to investigate the potential for targeting the NF-κB-inducing kinase, NIK, in two common B-cell malignancies, chronic lymphocytic leukemia (CLL) and multiple myeloma (MM). Using a selective NIK inhibitor, CW15337, we were able to demonstrate that cell lines an...

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Detalles Bibliográficos
Autores principales: Burley, Thomas A., Kennedy, Emma, Broad, Georgia, Boyd, Melanie, Li, David, Woo, Timothy, West, Christopher, Ladikou, Eleni E., Ashworth, Iona, Fegan, Christopher, Johnston, Rosalynd, Mitchell, Simon, Mackay, Simon P., Pepper, Andrea G. S., Pepper, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946537/
https://www.ncbi.nlm.nih.gov/pubmed/35326640
http://dx.doi.org/10.3390/cancers14061489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946537/
https://www.ncbi.nlm.nih.gov/pubmed/35326640
http://dx.doi.org/10.3390/cancers14061489

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