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Adenosine-Metabolizing Enzymes, Adenosine Kinase and Adenosine Deaminase, in Cancer

The immunosuppressive effect of adenosine in the microenvironment of a tumor is well established. Presently, researchers are developing approaches in immune therapy that target inhibition of adenosine or its signaling such as CD39 or CD73 inhibiting antibodies or adenosine A2A receptor antagonists....

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Detalles Bibliográficos
Autores principales: Zhulai, Galina, Oleinik, Eugenia, Shibaev, Mikhail, Ignatev, Kirill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946555/
https://www.ncbi.nlm.nih.gov/pubmed/35327609
http://dx.doi.org/10.3390/biom12030418