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The Clinical Concept of LTDpathy: Is Dysregulated LTD Responsible for Prodromal Cerebellar Symptoms?
Long-term depression at parallel fibers-Purkinje cells (PF-PC LTD) is essential for cerebellar motor learning and motor control. Recent progress in ataxiology has identified dysregulation of PF-PC LTD in the pathophysiology of certain types of immune-mediated cerebellar ataxias (IMCAs). Auto-antibod...
Autores principales: | Mitoma, Hiroshi, Yamaguchi, Kazuhiko, Honnorat, Jerome, Manto, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946597/ https://www.ncbi.nlm.nih.gov/pubmed/35326260 http://dx.doi.org/10.3390/brainsci12030303 |
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