Cargando…

Alpha-Synuclein-Specific Naturally Occurring Antibodies Inhibit Aggregation In Vitro and In Vivo

Parkinson’s disease (PD) is associated with motor and non-motor symptoms and characterized by aggregates of alpha-synuclein (αSyn). Naturally occurring antibodies (nAbs) are part of the innate immune system, produced without prior contact to their specific antigen, and polyreactive. The abundance of...

Descripción completa

Detalles Bibliográficos
Autores principales: Braczynski, Anne K., Sevenich, Marc, Gering, Ian, Kupreichyk, Tatsiana, Agerschou, Emil D., Kronimus, Yannick, Habib, Pardes, Stoldt, Matthias, Willbold, Dieter, Schulz, Jörg B., Bach, Jan-Philipp, Falkenburger, Björn H., Hoyer, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946620/
https://www.ncbi.nlm.nih.gov/pubmed/35327661
http://dx.doi.org/10.3390/biom12030469