NAMPT Inhibitor and P73 Activator Represses P53 R175H Mutated HNSCC Cell Proliferation in a Synergistic Manner

The p53 family has the following three members: p53, p63 and p73. p53 is a tumor suppressor gene that frequently exhibits mutation in head and neck cancer. Most p53 mutants are loss-of-function (LoF) mutants, but some acquire some oncogenic function, such as gain of function (GoF). It is known that...

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Detalles Bibliográficos
Autores principales: Cai, Bi-He, Bai, Zhi-Yu, Lien, Ching-Feng, Yu, Si-Jie, Lu, Rui-Yu, Wu, Ming-Han, Wu, Wei-Chen, Chen, Chia-Chi, Hsu, Yi-Chiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946684/
https://www.ncbi.nlm.nih.gov/pubmed/35327630
http://dx.doi.org/10.3390/biom12030438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946684/
https://www.ncbi.nlm.nih.gov/pubmed/35327630
http://dx.doi.org/10.3390/biom12030438

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