Occurrence of Total and Proteinase K-Resistant Alpha-Synuclein in Glioblastoma Cells Depends on mTOR Activity

SIMPLE SUMMARY: The accumulation of alpha-synuclein (α-syn) is considered a pathological hallmark of the neurodegenerative disorders known as synucleinopathies. The clearance of α-syn depends on autophagy activity, which is inhibited by the mechanistic target of rapamycin (mTOR). Thus, it is likely...

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Detalles Bibliográficos
Autores principales: Ryskalin, Larisa, Ferese, Rosangela, Morucci, Gabriele, Biagioni, Francesca, Busceti, Carla L., Michetti, Fabrizio, Lenzi, Paola, Frati, Alessandro, Fornai, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946689/
https://www.ncbi.nlm.nih.gov/pubmed/35326535
http://dx.doi.org/10.3390/cancers14061382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946689/
https://www.ncbi.nlm.nih.gov/pubmed/35326535
http://dx.doi.org/10.3390/cancers14061382

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