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Understanding the Notch Signaling Pathway in Acute Myeloid Leukemia Stem Cells: From Hematopoiesis to Neoplasia

SIMPLE SUMMARY: We review the state of the art of knowledge regarding the Notch signaling pathway to shed light on the role that this pathway has in hematopoiesis and hematological neoplasia, focusing on acute myeloid leukemia. ABSTRACT: The Notch signaling pathway is fundamental to early fetal deve...

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Detalles Bibliográficos
Autores principales: Láinez-González, Daniel, Serrano-López, Juana, Alonso-Dominguez, Juan Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946707/
https://www.ncbi.nlm.nih.gov/pubmed/35326610
http://dx.doi.org/10.3390/cancers14061459