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pncCCND1_B Engages an Inhibitory Protein Network to Downregulate CCND1 Expression upon DNA Damage

SIMPLE SUMMARY: Ewing sarcoma is a pediatric tumor characterized by chromosomal translocations, giving rise to the oncogene EWS-FLI1, which triggers the transcription of genes involved in neoplastic transformation including CCND1. In this work, we found that exposure to etoposide, a topoisomerase II...

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Detalles Bibliográficos
Autores principales: Palombo, Ramona, Paronetto, Maria Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946712/
https://www.ncbi.nlm.nih.gov/pubmed/35326688
http://dx.doi.org/10.3390/cancers14061537