Smo-Shh Agonist Purmorphamine Prevents Neurobehavioral and Neurochemical Defects in 8-OH-DPAT-Induced Experimental Model of Obsessive-Compulsive Disorder

Obsessive-compulsive disorder is a mental disorder characterized by repetitive, unwanted thoughts and behavior due to abnormal neuronal corticostriatal-thalamocortical pathway and other neurochemical changes. Purmorphamine is a smoothened-sonic-hedgehog agonist that has a protective effect against m...

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Detalles Bibliográficos
Autores principales: Gupta, Ria, Mehan, Sidharth, Sethi, Pranshul, Prajapati, Aradhana, Alshammari, Abdulrahman, Alharbi, Metab, Al-Mazroua, Haneen A., Narula, Acharan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946713/
https://www.ncbi.nlm.nih.gov/pubmed/35326298
http://dx.doi.org/10.3390/brainsci12030342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946713/
https://www.ncbi.nlm.nih.gov/pubmed/35326298
http://dx.doi.org/10.3390/brainsci12030342

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