Molecular dynamics study on the effects of charged amino acid distribution under low pH condition to the unfolding of hen egg white lysozyme and formation of beta strands

Aggregation of unfolded or misfolded proteins into amyloid fibrils can cause various diseases in humans. However, the fibrils synthesized in vitro can be developed toward useful biomaterials under some physicochemical conditions. In this study, atomistic molecular dynamics simulations were performed...

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Detalles Bibliográficos
Autores principales: Zein, Husnul Fuad, Alam, Ibrar, Asanithi, Piyapong, Sutthibutpong, Thana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946743/
https://www.ncbi.nlm.nih.gov/pubmed/35324907
http://dx.doi.org/10.1371/journal.pone.0249742