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Palmitate-Triggered COX2/PGE2-Related Hyperinflammation in Dual-Stressed PdL Fibroblasts Is Mediated by Repressive H3K27 Trimethylation

The interrelationships between periodontal disease, obesity-related hyperlipidemia and mechanical forces and their modulating effects on the epigenetic profile of periodontal ligament (PdL) cells are assumed to be remarkably complex. The PdL serves as a connective tissue between teeth and alveolar b...

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Detalles Bibliográficos
Autores principales: Schuldt, Lisa, Reimann, Michael, von Brandenstein, Katrin, Steinmetz, Julia, Döding, Annika, Schulze-Späte, Ulrike, Jacobs, Collin, Symmank, Judit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946768/
https://www.ncbi.nlm.nih.gov/pubmed/35326406
http://dx.doi.org/10.3390/cells11060955