Kv7 Channels in Cyclic-Nucleotide Dependent Relaxation of Rat Intra-Pulmonary Artery

Pulmonary hypertension is treated with drugs that stimulate cGMP or cAMP signalling. Both nucleotides can activate Kv7 channels, leading to smooth muscle hyperpolarisation, reduced Ca(2+) influx and relaxation. Kv7 activation by cGMP contributes to the pulmonary vasodilator action of nitric oxide, b...

Descripción completa

Detalles Bibliográficos
Autores principales: Al-Chawishly, Mohammed, Loveland, Oliver, Gurney, Alison M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946781/
https://www.ncbi.nlm.nih.gov/pubmed/35327621
http://dx.doi.org/10.3390/biom12030429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946781/
https://www.ncbi.nlm.nih.gov/pubmed/35327621
http://dx.doi.org/10.3390/biom12030429

Ejemplares similares