The Impact of NRF2 Inhibition on Drug-Induced Colon Cancer Cell Death and p53 Activity: A Pilot Study

Nuclear factor erythroid 2 (NF-E2) p45-related factor 2 (NRF2) protein is the master regulator of oxidative stress, which is at the basis of various chronic diseases including cancer. Hyperactivation of NRF2 in already established cancers can promote cell proliferation and resistance to therapies, s...

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Detalles Bibliográficos
Autores principales: Garufi, Alessia, Pistritto, Giuseppa, D’Orazi, Valerio, Cirone, Mara, D’Orazi, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946796/
https://www.ncbi.nlm.nih.gov/pubmed/35327653
http://dx.doi.org/10.3390/biom12030461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946796/
https://www.ncbi.nlm.nih.gov/pubmed/35327653
http://dx.doi.org/10.3390/biom12030461

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