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Downregulation and Hypermethylation of GABPB1 Is Associated with Aggressive Thyroid Cancer Features

SIMPLE SUMMARY: Promoter mutations of the telomerase reverse transcriptase (TERT) gene have been suggested as an oncogenic event in various cancers, including thyroid cancer (TC). GABPB1 is reported to activate TERT gene expression and has been proposed as a cancer therapeutic target. The aim of thi...

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Detalles Bibliográficos
Autores principales: Xing, Xiangling, Mu, Ninni, Yuan, Xiaotian, Wang, Na, Juhlin, C. Christofer, Strååt, Klas, Larsson, Catharina, Neo, Shi Yong, Xu, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946831/
https://www.ncbi.nlm.nih.gov/pubmed/35326537
http://dx.doi.org/10.3390/cancers14061385