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Downregulation and Hypermethylation of GABPB1 Is Associated with Aggressive Thyroid Cancer Features
SIMPLE SUMMARY: Promoter mutations of the telomerase reverse transcriptase (TERT) gene have been suggested as an oncogenic event in various cancers, including thyroid cancer (TC). GABPB1 is reported to activate TERT gene expression and has been proposed as a cancer therapeutic target. The aim of thi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946831/ https://www.ncbi.nlm.nih.gov/pubmed/35326537 http://dx.doi.org/10.3390/cancers14061385 |