Targeting BPTF Sensitizes Pancreatic Ductal Adenocarcinoma to Chemotherapy by Repressing ABC-Transporters and Impairing Multidrug Resistance (MDR)

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma is a devastating disease and an extremely chemoresistant tumour. In the present manuscript, we described the role of BPTF during tumour pancreatic ductal adenocarcinoma progression and in response to gemcitabine treatment, a gold standard treatment in...

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Detalles Bibliográficos
Autores principales: Muñoz Velasco, Raúl, Jiménez Sánchez, Paula, García García, Ana, Blanco Martinez-Illescas, Raquel, Pastor Senovilla, Ángela, Lozano Yagüe, Marian, Trento, Alfonsina, García-Martin, Rosa María, Navarro, Diego, Sainz, Bruno, Rodríguez Peralto, José Luis, Sánchez-Arévalo Lobo, Víctor Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946837/
https://www.ncbi.nlm.nih.gov/pubmed/35326669
http://dx.doi.org/10.3390/cancers14061518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946837/
https://www.ncbi.nlm.nih.gov/pubmed/35326669
http://dx.doi.org/10.3390/cancers14061518

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