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Mesothelin: An Immunotherapeutic Target beyond Solid Tumors

SIMPLE SUMMARY: This review summarizes the current knowledge on mesothelin’s function, its role in cancer, and opportunities for immunotherapeutic targeting of mesothelin. Immunotherapies including monoclonal antibodies, antibody–drug conjugates, chimeric antigen receptor T and NK-cells, targeted al...

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Detalles Bibliográficos
Autores principales: Faust, Joshua R., Hamill, Darcy, Kolb, Edward Anders, Gopalakrishnapillai, Anilkumar, Barwe, Sonali P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946840/
https://www.ncbi.nlm.nih.gov/pubmed/35326701
http://dx.doi.org/10.3390/cancers14061550