Detection of NTRK Fusions and TRK Expression and Performance of pan-TRK Immunohistochemistry in Routine Diagnostics: Results from a Nationwide Community-Based Cohort

Gene fusions involving NTRK1, NTRK2, and NTRK3 are rare drivers of cancer that can be targeted with histology-agnostic inhibitors. This study aimed to determine the nationwide landscape of NTRK/TRK testing in the Netherlands and the usage of pan-TRK immunohistochemistry (IHC) as a preselection tool...

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Detalles Bibliográficos
Autores principales: Koopman, Bart, Kuijpers, Chantal C. H. J., Groen, Harry J. M., Timens, Wim, Schuuring, Ed, Willems, Stefan M., van Kempen, Léon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946871/
https://www.ncbi.nlm.nih.gov/pubmed/35328221
http://dx.doi.org/10.3390/diagnostics12030668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946871/
https://www.ncbi.nlm.nih.gov/pubmed/35328221
http://dx.doi.org/10.3390/diagnostics12030668

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