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Extracellular Vesicle-Mediated IL-1 Signaling in Response to Doxorubicin Activates PD-L1 Expression in Osteosarcoma Models

The expression of programmed cell death ligand 1 (PD-L1) in tumors is associated with tumor cell escape from T-cell cytotoxicity, and is considered a crucial effector in chemoresistance and tumor relapse. Although PD-L1 induction has been observed in patients after chemotherapy treatment, the mechan...

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Detalles Bibliográficos
Autores principales: Yati, Su, Silathapanasakul, Atiruj, Thakaeng, Chakrarin, Chanasakulniyom, Mayuree, Songtawee, Napat, Porntadavity, Sureerut, Pothacharoen, Peraphan, Pruksakorn, Dumnoensun, Kongtawelert, Prachya, Yenchitsomanus, Pa-thai, Chanmee, Theerawut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946890/
https://www.ncbi.nlm.nih.gov/pubmed/35326493
http://dx.doi.org/10.3390/cells11061042