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A Temporary Pause in the Replication Licensing Restriction Leads to Rereplication during Early Human Cell Differentiation

Gene amplifications in amphibians and flies are known to occur during development and have been well characterized, unlike in mammalian cells, where they are predominantly investigated as an attribute of tumors. Recently, we first described gene amplifications in human and mouse neural stem cells, m...

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Detalles Bibliográficos
Autores principales: Minet, Marie, Abu-Halima, Masood, Du, Yiqing, Doerr, Julia, Isted, Christina, Ludwig, Nicole, Keller, Andreas, Meese, Eckart, Fischer, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946923/
https://www.ncbi.nlm.nih.gov/pubmed/35326512
http://dx.doi.org/10.3390/cells11061060