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SWI/SNF Antagonism of PRC2 Mediates Estrogen-Induced Progesterone Receptor Expression

Endometrial cancer (EC) is characterized by high estrogen levels unopposed by progesterone. Treatment with progestins is standard for early EC, but the response to progestins is dependent on progesterone receptor (PGR) expression. Here, we show that the expression of PGR in endometrial epithelial ce...

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Detalles Bibliográficos
Autores principales: Wilson, Mike R., Reske, Jake J., Koeman, Julie, Adams, Marie, Joshi, Niraj R., Fazleabas, Asgerally T., Chandler, Ronald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946988/
https://www.ncbi.nlm.nih.gov/pubmed/35326450
http://dx.doi.org/10.3390/cells11061000